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Sexual Differentiation in Domestic Animals - Flow Chart

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Sexual Differentiation in Domestic Animals - Flow Chart

Andrological Horoscope

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  Andrological Horoscope -  Listen To Your Fingers You may have noticed the persons on roadsides who are predicting the future of persons by seeing their palm line pattern. I do not have an answer to prove the possibility of predicting the future of a person by their palm. However, I am going to tell how you can know about your past by the length of your fingers. Past means not about your previous year’s life, this is far beyond that. I am going to predict what was happened when you are inside your mother’s womb.  Is this sound interesting? Yes, by measuring the length of your fingers, you can find out whether you had been exposed to a higher level of male hormone (testosterone) when you are inside your mother’s womb. This is not like a simple palm line horoscope because so many scientific literatures are available and new researches also still going on in this aspect.   2D:4D ratio How to measure?        ...

Terms used in equine reproduction

                   COMMON TERMS USED IN                              EQUINE REPRODUCTION Maiden mare Female equine over two years of age that has not been covered by a stallion. The term filly could also be used with the female that is 2 or 3 years of age. Barren mare A mare bred several cycles in a season without pregnancy or lost pregnancy. Open mare A   mare that has had foals previously but is not pregnant now. Nightmare Don't get confused by this word by correlate with horses. However does not related to the horses. Rather, the word is derived from mara, a scandinavian mytholigical term referring to a spirit sent to suffocate sleepers. The early meaning of nightmare included the sleeper’s experience of...

ARCHE - The beginning

Gonadarche              1. Arche is the Greek word. Arche- beginning              2. Gonadarche refers to the earliest changes of puberty.               3. In response to pituitary gonadotropins, the ovaries in female and the testes in male begin to grow and increase the production of the sex steroids, especially estradiol and testosterone.              4. In male, testicular enlargement is the first phyical sign of gonadarche, and usually of puberty.              5. In female, ovarian growth cannot be directly seen, so thelarche and growth acceleration are usually the first evidence of gonadarche.              6. Gonadarche indicates that true central puberty has begun, while adrenarche is an independent process only loosely associated with complete puberty. ...

DE - SYNCHRONY THEORY

                         DE - SYNCHRONY THEORY OF PUBERTY   This theory is based on a finding that GnRH concentrations in the hypothalamus during prepuberty are comparable to those in the adult animals.   GnRH from the hypothalamus is controlled by an area in the hypothalamus referred to as the neural GnRH pulse generator.     Age related changes in brain morphology and neuronal cytoarchitecture may also be important. Theory Desynchrony theory proposes that the lack of GnRH stimulation of the pituitary in prepubertal animal is a result of the desynchronization of the discharge or 'firing' of the GnRH secreting neurons.  This hypothesis has some support from in vitro studies in immortalized GnRH neurons.                                       

INTRINSIC RESTRAINT THEORY

Central nervous system (CNS) restraint hypothesis of puberty "In the 1980s, it was found that agonadal subjects had a pattern of changes in gonadotropin concentration. It was  called as intrinsic restraint hypothesis" In addition to sex steroid-mediated negative feedback, a central inhibitory system restrains GnRH release and maintains the  prepubertal  phase.   At the onset of puberty, the intrinsic CNS restraint is inhibited or is dominated by a stimulatory system.   During the last decades, considerable evidence has been gathered to support this intrinsic restraint hypothesis. Factors involved in the regulation of gonadotropin-releasing hormone (GnRH) secretion: Intrinsic restraints:     1. GABA (Gamma Amino Butyric Acid) Stimulators:     1. Glutamate     2. NPY     3. Leptin     4. TNF alpha       According to this idea, GnRH secretion is quiescent in ch...

GONADOSTAT THEORY

GONADOSTAT THEORY OF PUBERTY:      The gonadostat theory was proposed by Hohlweg , 1931     1. During prepuberty, sensitivity to the negative feedback actions of gonadal steroids is highest, resulting in a low release of GnRH and gonadotropins.      2. Initiation of puberty is secondary to a decrease in sensitivity to gonadal steroid feedback inhibition , resulting in increased GnRH and gonadotropin release, until a new equilibrium level is reached in adulthood. Example:        Failure of prepubertal ewe lamb to undergo ovulation and oestrus is due to the high threshold for the positive feedback is lowered, thus there is no LH surge. At puberty, the threshold is lowered, thus allowing the pituitary to respond.